One study of 60 healthy female volunteers found that supplementation with L-glutathione for 12 weeks led to significant reductions in skin melanin index and skin darkening, as well as improvements in skin brightness and radiance
Singh R, Singh S, Parihar P, Mishra RK, Tripathi DK, Singh VP, Chauhan DK, Prasad SM (2016) Reactive oxygen species (ROS): beneficial companions of plants developmental processes
Conversely, ferroptosis can be blocked by modulating enzymes involved in the biosynthesis of lipid peroxidation (Yuan et al., 2016)
Many protocols combine both approaches for maximum effect, typically running 12 to 16 weeks minimum before visible density changes become apparent
Radiant Skin & Anti-Aging: The Science of the Glow Many seek glutathione for its positive impact on skin health